Voltage and Current Clamp Transients with Membrane Dielectric Loss
نویسندگان
چکیده
منابع مشابه
Voltage and current clamp transients with membrane dielectric loss.
Transient responses of a space-clamped squid axon membrane to step changes of voltage or current are often approximated by exponential functions of time, corresponding to a series resistance and a membrane capacity of 1.0 muF/cm(2). Curtis and Cole (1938, J. Gen. Physiol.21:757) found, however, that the membrane had a constant phase angle impedance z = z(1)(jomegatau)(-alpha), with a mean alpha...
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,4BSTRACT TASAKI, I. AND C. S. SPYROPOULOS. Membrane conductance and currentvoltage relation in the squid axon under ‘voltage-clamp.’ &L-The conductance of the squid axon membrane under ‘voltage-clamp’ was measured by superposing a sinusoidal wave upon rectangular clamping voltage pulses. It was possible to determine the time course of the emf of the membrane under ‘voltage-clamp’ on a single p...
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The sucrose-gap method introduced by Stämpfli provides a means for the application of a voltage clamp to the lobster giant axon, which responds to a variety of different experimental procedures in ways quite similar to those reported for the squid axon and frog node. This is particularly true for the behavior of the peak initial current. However, the steady state current shows some differences....
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Ionic mechanisms of excitation were studied in the immature egg cell membrane of a starfish, Mediaster aequalis, by analyzing membrane currents during voltage clamp. The cell membrane shows two different inward current mechanisms. One is activated at a membrane potential of -55 approximately -50 mV and the other at -7 approximately -6 mV. They are referred to as channels I and II, respectively....
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1973
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(73)86050-3